1. Roles at cellular and molecular level
Types
Carbohydrates
- Important source of energy
- Provide energy to muscles- carbs have a protein-sparing action (prevent protein catabolising to provide glucose when carb levels are low and hence, can preserve muscle tissue)
- Allows protein to perform its function (development and maintenance of muscle mass)
- Healthy function of the CNS (CNS depends on glucose)
- Components of glycolipids, glycoprotein and nucleic acids
- Provide fiber:
- Insoluble fiber increases stool weight, promoting regular elimination of waste and prevent constipation
- Soluble fibre: food source for gut bacteria
- Fermentation of soluble fiber results in release of short chain fatty acids and B vitamins
- Short chain FA block cholesterol synthesis in the liver
- Reduce cholesterol by enhancing hepatic control to bile acid
- Reduce postprandial rise in blood glucose
- Delay gastric emptying and increase satiation
- Provide desirable flavor and texture in food products
Health issues
- dental carries
- obesity
- CVD
- Colorectal cancer
Protein
- Growth and maintenance
- Cell structure
- Antibodies and hormone production
- Source of energy
- Maintenance of fluid balance
Fat
- source of energy
- Supply of EFA
- cell structure- PL
- Required for absorption of fat soluble vitamins
- increase palatability
Deficient of macronutrient
Carbs- increase in ketone bodies production, protein-tissue wasting
Protein- protein energy malnutrition- kwashiorkor and marasmus
Fat- weight loss, can't keep warm, lack of EFA and Vit ADEK
Excessive intake of macronutrient
Carbs- too much triglycerides in blood
Protein- proteins consumed in excess is deaminated, and the resulting carb skeletons are metabolised to provide energy/ acetyl CoA for fatty acid synthesis. Excess protein is eliminated form the body as urinary nitrogen, and is accompanied by increasing urinary calcium, leading to osteoporosis, gout etc
Fat- increased cholestrol levels leading to CVD
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My name is Ivan and I have just had the worst years of my life, but now I hope I’m looking at a much
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